Curriculum Vitae
Selections: Personal Info | Education | Professional Memberships |
Professional Experience | Grants | Honors | Workshops |
Service | Teaching | Journal Reviewer | Grant Review |
Publications | Ph.D Graduates | Graduate Commitee | Undergraduate Commitee |
Presentations | Selected Posters | Invited Colloquia | Media Interactions
Personal Information
Date of birth: October 10, 1968
Marital Status: Married, three children
Education
1999 Post-doctoral Research Fellow
Laboratory of Dr. A. Leslie Morrow
University of North Carolina-Center for Alcohol Studies
1996 Post-doctoral Research Associate
Laboratory of Dr. Peter Simson
Miami University
1996 Ph. D., Psychology
Miami University
Dr. Phillip J. Best, advisor
1994 M.A., Psychology
Miami University
1991 B.S., Psychology/Biology (cum laude)
Southwest Missouri State University
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Professional Memberships
Research Society in Alcoholism
Professional Experience
2007–present Associate Professor, with tenure
Baylor University
Department of Psychology and Neuroscience
2007 Visiting Associate Professor
National University of Singapore
Top 20 university in the world
2003–2007 Director
Tennessee Center for Addiction Research
2003–2007 Board of Directors
Tennessee Biotechnology Association
University of Memphis Representative
2003–2007 Associate Professor, with tenure
Department of Psychology
The University of Memphis
2003–2007 Adjunct Assistant Professor
Anatomy and Neurobiology
University of Tennessee Health Science Center
2001–2007 Feinstone Center for Genomic Research
Member
The University of Memphis
1999–2003 Assistant Professor
Department of Psychology
The University of Memphis
1996-1999 Postdoctoral Research Fellow (Laboratory Manager)
University of North Carolina-Center for Alcohol Studies
1992-1996 Graduate Research Assistant
Miami University
Laboratory of Dr. Phillip J. Best
1992-1995 Graduate Teaching Assistant
Miami University
1991-1992 Graduate Teaching Assistant
University of Memphis
1989-1991 Undergraduate Tutor, Statistics
Southwest Missouri State University
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Grants
National Institute on Alcohol Abuse and Alcoholism: National Research Service Award
(1 F31 AA05414-01A1). Prenatal Ethanol: Place Cell and Spatial Memory Effects.
Principal Investigator $13,008.00 total cost
National Institute on Alcohol Abuse and Alcoholism: National Research Service Award
(1 F32-AA05519-01). GABAergic Adaptations to Ethanol Self-administration.
Principal Investigator $56,336.00 total cost
Alcoholic Beverage Medical Research Foundation (06/01/00 – 05/30/02)
The neuroactive steroid 3a-hydroxy-5a-pregnan-20-one modulates ethanol-induced
decreases in spatial cognitive processing.
Principal Investigator $80,000.00 total cost
University of Memphis Faculty Award (06/01/00 – 05/30/01)
Effects of the neuroactive steroid 3[a]-hydroxy-5[a]-pregnan-20-one on spatial
cognitive processing in the rat.
Principal Investigator $4,000.00
National Institute of Health (9/25/00- 8/30/05)
(1 U01 MH61971-01) Targeted mutagenesis of the mouse genome and neural phenotype
Principal Investigator Dan Goldwitz, UT-Memphis Medical Center
$12,774,513.00 total costs
Investigator and Co-Director of Alcohol Core
$1,277,515.00 Total cost to the University of Memphis
University of Memphis Faculty Award (06/01/01-05/30/02)
Effects of de novo blockade of the neuroactive steroid 3[a]-hydroxy-5[a]-pregnan-20-one
on ethanol induced spatial working memory impairments.
Principal Investigator $4,000.00
National Institute on Alcoholism and Alcohol Abuse (02/01/02 – 1/31/07)
INIA: Systems Mechanism in Alcohol-Stress Interaction
Principal Investigator $1,378,312.00 total cost
University of Tennessee Health Science Center (01/01/04 – 12/31/04)
Mouse Husbandry
Principal Investigator $15,000.00
University of Memphis Faculty Award ((7/01/04 – 6/30/05)
The effect of ethanol consumption on physiology and gambling behavior: identifying
mechanisms to encourage effective self-regulation.
Principal Investigator $6,000.00
National Institute on Alcoholism and Alcohol Abuse (9/18/04 – 9/17/07)
GABAa receptor g[2] knockout: ethanol and spatial memory
Principal Investigator $381,750
National Institute on Alcoholism and Alcohol Abuse (11/01/04-10/31/09)
Ethanol mechanisms in GABAAR gene targeted mice
Subcontract from U of Pittsburgh
PI on Subcontract $278,456
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Honors
Excellence in Teaching Award, College of Arts & Sciences, University of Memphis, 2005
Participate, Society for Neuroscience Press Conference on the Adolescent Brain, 2003.
T.W. Briggs Foundation Excellence in Teaching Award -- Nominated
Young Investigator Award – Research Society on Alcoholism, 2002
External Reviewer – Baylor University Department of Psychology and Neuroscience
Early Career Research Award – University of Memphis, 2001.
Junior Faculty Travel Award – American Society for Biochemistry and Molecular Biology
Ethanol and Cell Signaling, Oct. 1999.
NIAAA Post-doctoral Fellowship (1 F32-AA05519-01), 1998-1999.
Neurobiology Training Grant Recipient-UNC-Chapel Hill 1997-1998.
NIAAA Pre-doctoral Fellowship (1 F31 AA05414-01A1), 1996.
Dissertation Fellowship, Miami University--Psychology, 1995-1996.
Research Society on Alcoholism--Junior Investigator Award, June 1997.
Research Society on Alcoholism/International Society for Biomedical Research on Alcoholism
Graduate Student Travel Award, June 1996.
Jeff Stein Graduate Fellowship, May 1994--$1,000.00.
Achievement Awards, Miami University, 5 awards totaling $1,250.00.
Abstract selected by the Committee on National Advocacy of the Research Society on
Alcoholism for distribution to national news services and media representatives.
Capretta Memorial Scholarship for Outstanding Graduate Student in Psychology, April 1996.
Letters of Commendation, Miami Psychology Department, 1993, 1994, 1995, 1996.
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Workshops
Experimental Neurogenetics of the Mouse, 2004 - 2006, Memphis TN
Organizer and Faculty
10th Summer School on Behavioral Neurogenetics, August 8-14, 2004, Memphis TN
Organizer and Faculty
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Service
Program Committee Member, Research Society on Alcoholism, 2007
Tenure and Promotion Committee member, Dr. Charles Blaha, 2007
Animal Facilities Committee, Chair, 2007
Center of Excellence External Reviewer - U.S. Army Medical Research and Materiel Command
Review of Center from the Ernest Gallo Clinic and Research Center
entitled "Translational Center for the Study of Alcoholism and Substance Abuse, 2003.
Faculty Advisory Committee: 2001-present, University of Memphis
Personnel Committee: 2002-2003, University of Memphis
Undergraduate Curriculum: 1999-present, University of Memphis
Chair, 2002 to present
Newsletter Committee: 2001-present, University of Memphis
Colloquium Committee: Biopsychology representative 1993-1994 Miami University
Graduate Committee: Graduate student representative 1994-1995 Miami University
Steering Committee: Graduate student representative 1995-1996 Miami University
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Teaching
Introduction to Biopsychology. Miami University, Oxford OH
Introduction to Statistics. University of North Carolina – Chapel Hill
University of Memphis
Introduction to Biopsychology. University of Memphis, Memphis TN.
Introduction to Psychology, University of Memphis, Memphis TN.
Alcohol, Drugs and Behavior, University of Memphis, Memphis TN
Alcohol, Drugs and Behavior, Honors, University of Memphis, Memphis TN
Neurobiology of Learning and Memory, University of Memphis, Memphis TN
Introduction to Statistics, University of Memphis, Memphis TN
Alcohol, Drugs and Behavior, National University of Singapore, Singapore
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Journal Reviewer
Journal of Pharmacology and Experimental Therapeutics
Hippocampus
Neuroscience
Pharmacology, Biochemistry & Behavior
Neurobiology of Learning and Memory
Wadsworth Publishing
Neuropharmacology
Alcoholism: Clinical and Experimental Research
Brain Research
Behavioural Brain Research
Developmental Brain Research
Journal of Neurochemistry
Alcohol
European Journal of Neuroscience
Brain, Genes and Behavior
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Grant Reviewer
AA-1, National Institute on Alcohol and Alcoholism, Study Section Member 2007-2009.
National Center for Research Resources, Minority Center Review, Florida A&M University, 2007.
National Institute on Alcohol and Alcoholism, Ad hoc reviewer for SEP, Neuroscience, 2007.
United States Army Medical Research and Materiel Command reviewer (2006, 2007).
National Institute on Alcohol and Alcoholism, Ad hoc reviewer for AA1(April and October),
DD60, and DD80 2006.
Interactive Neuroscience Initiative on Alcoholism, Pilot Project Grant Reviewer, 2003.
Center of Excellence External Reviewer - U.S. Army Medical Research and Materiel Command
Review of Center from the Ernest Gallo Clinic and Research Center entitled
"Translational Center for the Study of Alcoholism and Substance Abuse, 2003, 2005.
Scientific Review Board
Institute for the Study of Aging 2002-2005
Wellcome Trust Foundation 2003, 2005
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Publications
Matthews, D.B. & Best, P.J. (1995). Fimbria/fornix lesions facilitate the learning
of a non-spatial response task. Psychonomic Bulletin & Review, 2(1), 113-116. 35 citations.
Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Acute ethanol impairs the use of
spatial memory but not the use of stimulus/response memory in the rat. Alcoholism: Clinical
and Experimental Research, 19(4), 902-909. 54 citations
Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Impaired spatial memory in rats after acute ethanol
exposure. Alcoholism: Clinical and Experimental Research, 19(4), Highlights.
Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Ethanol alters the spatial processing of hippocampal
place cells: a mechanism for impaired navigation when intoxicated. Alcoholism: Clinical and
Experimental Research, 20(2), 404-407. 27 citations
Matthews, D.B., Best, P.J., White, A.M., Vandergriff, J. & Simson, P.E., (1996). Ethanol impairs
spatial cognitive processing: new behavioral and electrophysiological findings. Current Directions
in Psychological Science, 5(4), 111-115. 9 citations
Matthews, D.B. & Best, P.J. (1997). Evidence for the flexible use of spatial knowledge in the rat.
Psychobiology, 25(4), 294-302. 13 citations
Matthews, D.B., Devaud, L.L., Fritschy, J.M., Sieghart, W. & Morrow, A.L. (1998). Differential regulation
of GABAA receptor gene expression by ethanol in the rat hippocampus vs. cerebral cortex. Journal of
Neurochemistry, 70, 1160-1166. 46 citations
Matthews, D.B. & Simson, P.E. (1998). Prenatal exposure to ethanol disrupts spatial memory: effect of
the training-testing delay period. Physiology & Behavior, 64(1), 63-67. 14 citations
Grobin, A.C., Matthews, D.B., Devaud, L.L. & Morrow, A.L. (1998). The role of GABAA receptors in the
acute and chronic effects of ethanol. Psychopharmacology, 139(1/2), 2-19. 194 citations
Matthews, D.B. & Uhler-Dietz B. (1998). The black sheep effect: how positive and negative advertisements
affect voters’ perceptions of the sponsor of the advertisement. Journal of Applied Social Psychology,
28, 1902-1914. 3 citations
Matthews, D.B., Illgen, M.A., White, A.M. & Best, P.J. (1999). Acute ethanol administration impairs
spatial performance while facilitating non-spatial performance in rats. Neurobiology of Learning and
Memory, 72, 169-179. 28 citations
Davaud, L. L., Matthews, D. B. & Morrow, A. L. (1999). Gender impacts behavioral and neurochemical
adaptations in ethanol dependent rats. Pharmacology, Biochemistry & Behavior. 64, 841-849. 26 citations
Morrow, A.L., Janis, G.L., Van Doren, M.J., Matthews, D.B., Samson, H.H., Janis, P. & Grant, K.A. (1999).
Neurosteroids mediate pharmacological effects of ethanol: A new mechanism of ethanol action?
Alcoholism: Clinical and Experimental Research, 23, 1933-1940. 53 citations
VanDoren, M.J., Matthews, D.B., Janis, G.C., Grobin, A.C., Devaud, L.L & Morrow, A.L. (2000).
Neuroactive steroid 3a-hydroxy-5a-Pregnan-20-one modulates behavioral and electrophysiological actions
of ethanol. Journal of Neuroscience, 20, 1982-1989. 131 citations
Matthews, D.B. & Morrow, A.L. (2000). The effects of acute and chronic ethanol exposure on spatial cognitive
processing and hippocampal function in the rat. Hippocampus, 10, 122-130. 21 citations
White, A.M., Matthews, D.B. & Best, P.J. (2000). Ethanol, memory and hippocampal function: A review of
recent findings. Hippocampus, 10, 88-93. 50 citations
Matthews, D.B. (2000). Ethanol and the hippocampal system: behavior to molecular biology.
Hippocampus, 10, 87. 1 citation
Matthews, D.B., Kralic, J. E., Devaud, L.L., Fritschy, J.M. & Morrow, A.L. (2000). Chronic blockade of
N-methyl-D-aspartate receptors alters g-Aminobutyric acid type A receptor gene expression and
function in the rat. Journal of Neurochemistry, 74, 1522-1528. 15 citations
Kampov-Polevoy, A.B, Matthews, D.B., Gause, L., Morrow, A.L. & Overstreet, D.H. (2000). Development of
physical dependence upon alcohol in p rats: changes in seizure thresholds, anxiety and patterns of alcohol
drinking. Alcoholism: Clinical and Experimental Research, 24, 278-284. 39 citations
Matthews, D.B., Criswell, H.E., Grobin, A.C. & Morrow, A.L. (2000). Chronic ethanol consumption alters
recovery of spontaneously active medial septal/diagonal band of Broca neurons from GABA-microiontophoresis.
Alcoholism: Clinical and Experimental Research, 24, 1427-1432. 0 citations
Matthews, D.B., Overstreet, D.H., Rezvani, A.H., Devaud, L.L. & Morrow, A.L. (2001). Comparisons of
sweetened ethanol solutions on ethanol self-administration and blood ethanol levels. Pharmacology,
Biochemistry & Behavior, 68, 13-21. 9 citations
Hoffmann, S.E. & Matthews, D.B. (2001). Ethanol-induced impairments in spatial working memory are
not due to deficits in learning. Alcoholism: Clinical and Experimental Research, 25, 856-861. 8 citations
Grobin, A.C., Matthews, D.B., Montoya, D., Wilson, W.A., Morrow, A.L., & Swartzwelder, H. S. (2001).
Age related differences in neurosteroid potentiation of muscimol-stimulated 36Cl- flux following chronic
ethanol treatment. Neuroscience, 105, 547-552. 7 citations
Morrow, A.L., VanDoren M.J., Penland, S.N. & Matthews, D.B. (2001). The Role of GABAergic Neuroactive
Steroids in Ethanol Action, Tolerance and Dependence. Brain Research Reviews, 37, 98-109. 78 citations
Matthews, D.B., Morrow, A.L., Tokunaga, S. & McDaniel, J.R. (2002). Acute ethanol administration and
acute allopregnanolone administration impair spatial memory in the Morris water task. Alcoholism: Clinical
and Experimental Research, 26, 1747-1751. 22 citations
Tokunage, S., McDaniel, J.R., Morrow, A.L. & Matthews, D.B. (2003). Effect of acute ethanol administration
and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity.
Brain Research, 967, 273-280. 18 citations
Mittleman, G. Van Drunt, C.L. & Matthews D.B. (2003). Schedule induced ethanol self-administration in
DBA/2J and C57BL/6J. Alcoholism: Clinical and Experimental Research, 27, 918-925. 16 citations
Morrow, A.L., Khisti, R.T., Tokunaga, S., McDaniel, J.R., Matthews, D.B. (2003). GABAergic Neuroactive
steroids modulate selective ethanol actions: Mechanisms and significance. In: Neurosteroid Effects in the
Central Nervous System: The Role of the GABAA Receptor, Smith, S.H. (Ed.) CRC Press LLC, Miami,
pp. 219-245 (2003). 0 citations
Silvers, J.M., Tokanaga, S., Mittleman, G. & Matthews D.B. (2003). Chronic intermittent ethanol exposure
during adolescence produces metabolic, hypnotic and cognitive tolerance in rats. Alcoholism: Clinical
and Experimental Research, 27, 1606-1612. Highlighted article is issue. 2 citations
The Complex Trait Consortium (CTC)* (2003). Lorraine Flaherty, Oduola Abiola, Joe M. Angel, Philip Avner,
Alexander A. Bachmanov, John K. Belknap, Beth Bennett, Elizabeth P. Blankenhorn, David A. Blizard,
Valerie Bolivar, Gudrun A. Brockmann, Kari J. Buck , Jean-Francois Bureau, William L. Casley, Elissa J. Chesler,
James M. Cheverud, Gary A. Churchill, Melloni Cook, John C. Crabbe, Wim E. Crusio Ariel Darvasi,
Gerald de Haan Peter Demant, R.W. Doerge, Rosemary W. Elliott, Charles R. Farber, Jonathan Flint,
Howard Gershenfeld, John P. Gibson, Weikuan Gu25, Heinz Himmelbauer26, Robert Hitzemann6, Hui-Chen Hsu27,
Kent Hunter28, Fuad Iraqi24, Ritsert C. Jansen, Thomas E. Johnson, Byron C. Jones, Gerd Kempermann,
Frank Lammert, Lu Lu, Kenneth F. Manly, Douglas B. Matthews, Juan F. Medrano, Margarete Mehrabian,
Guy Mittleman, Beverly A. Mock, Jeffrey S. Mogi4, Xavier Montagutelli, Grant Morahan, John D. Mountz ,
Hiroki Nagase, Richard S. Nowakowski7, Bruce F. O'Hara, Alexander V. Osadchuk, Beverly Paigen,
Abraham A. Palmer, Jeremy L Peirce, Daniel Pomp, Michael Rosemann, Glenn D. Rosen, Leonard C. Schalkwyk,
Ze'ev Seltzer, Stephen Settle, Kazuhiro Shimomura, Siming Shou, James M. Sikela, Linda D. Siracusa,
Jimmy L. Spearow, Cory Teuscher, David W. Threadgill, Linda A. Toth, Ayo A. Toye, Csaba Vadasz,
Gary Van Zant Edward, Wakeland, Robert W. Williams, , Huang-Ge Zhang, Fei Zou (2003). The nature and
identification of quantitative trait loci: a community’s view. Nature Genetics Reviews, 4, 911-915.
90 citations
Silvers, J. M., Tokunaga, S., Berry, R.B., White, A.M. & Matthews D.B. (2003). Impairments in spatial
learning and memory: ethanol, allopregnanolone and the hippocampus. Brain Research Review 967, 273-280.
15 citations
Berry, R.B. & Matthews, D.B. (2004). Acute ethanol administration selectively impairs spatial memory in
C57BL/6J Mice. Alcohol, 32, 9-18. 9 citations
Khisti, R.T., VanDoren, M.J., Matthews, D. B. & Morrow A.L. (2004). Ethanol-induced elevation of
3a-hydroxy-5a-pregnan-20-one does not modulate motor in-coordination in rats. Alcoholism:
Clinical and Experimental Research, 28, 1249-1256. 4 citations
Matthews, D.B. & Silvers, J.R. (2004). The use of acute ethanol administration as a tool to investigate
multiple memory systems. Neurobiology of Learning and Memory. 82, 299-308. Invited Review. 3 citations
The Complex Trait Consortium (2004) Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD,
Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M,
Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF,
Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G,
Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC,
Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F,
Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR,
Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H,
Nowakowski RS, O'hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L,
Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC,
Seltzer Z, Shimomura K, Shou S, Sillanpaa MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM,
Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D,
Zhang M, Zou F. The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Nature Genetics, 36, 1133-1137. 72 citations
Matthews, D.B. (2004). Neuroactive steroids and ethanol-induced decreases in spatial cognitive processing.
Proceedings of the 31st International Medical Advisory Group Conference, 31, 85-90. 0 citations
Kralic, J.E., Criswell, H.E., Osterman, J., O’Buckley, T.K., Matthews, D.B., Hamre, K., Breese, G.R.,
Homanics, G.E. & Morrow, A.L. (2005). Genetic essential tremor in GABAA a1 subunit knockout mice.
Journal of Clinical Investigation, 115: 774-779. 25 citations
Matthews, D.B., Bhave, S.V., Belknap, J.K., Brittingham, C., Chesler, E.J., Hitzemann, R.J., Hoffmann, P.L.,
Lu, L., McWeeney, S., Miles, M.F., Tabakoff, B. & Williams, R.W. (2005). Complex genetics of
interactions of alcohol and CNS function and behavior. Alcoholism: Clinical and Experimental Research,
29: 1706-1719. 0 citations
Tokunaga, S., Silvers, J. & Matthews, D.B. (2006). Chronic intermittent ethanol exposure during
adolescence blocks ethanol-induced inhibition of spontaneously active hippocampal pyramidal neurons.
Alcoholism: Clinical and Experimental Research, 30, 1-6. 2 citations
Goldowitz, D., Matthews, D.B., Hamre, K.M., Mittleman, G., Chesler, E.J., Becker H. C., Lopez,
M.F., Jones, S.R.,Mathews, T.A., Miles, M.F., Kerns, R. & Grant, K.A. (2006). Progress in using mouse
inbred strains, consomics and mutants to identify genes related to stress, anxiety and alcohol phenotypes.
Alcoholism: Clinical and Experimental Research, 30, 1066-1078. 1 citations
Werner, D.F., Blednov, Y.A., Ariwodola, O.J., Silberman, Y., Logan, E., Berry, R.B., Borghese, C.,
Matthews, D.B.,Weiner, J.L., Harrison, N.L., Harris, R.A., Homanics, G.E. (2006). Knock-in mice
with ethanol-insensitive alpha1-containing GABAA receptors display selective alterations in behavioral
responses to ethanol, Journal of Pharmacology and Experimental Therapeutics, 319, 219-227. 1 citation
Silvers, J.M., Tokunaga, S., Mittleman, G., O’Buckley, T., Morrow, A.L. & Matthews, D.B. (2006).
Chronic intermittent ethanol exposure during adolescence reduces the effect of ethanol challenge on
hippocampal allopregnanolone levels and Morris water maze task performance, Alcohol, 151-158. 0 citations
Hamre, K.M, Wilkenson, S., Goldowitz, D.G. & Matthews, D.B. (2007). Screening for ENU-Induced
mutations in mice that result in aberrant ethanol-related phenotype. Behavioral Neuroscience, 121,
665-678. 0 citations
Goa, J., Maison, S.F., Wu, X., Hirose, K., Jones, S.M., Bayazitov, I., Tian, Y., Mittleman, G.,
Matthews D.B., Zakharenko, S., Liberman, M.C. & Zuo, J. (2007). The orphan glutamate
receptor [d]1 subunit is required for high-frequency hearing. Molecular Cellular Biology, 27, 4500-4512.
0 citations
Tinsley, K.L., Silvers, J.M., Tokunaga, S & Matthews, D.B. (submitted). Adolescent binge-like exposure
to moderate dose alcohol produces tolerance to a high dose alcohol challenge in adulthood: Implications
for teen alcohol consumption. Alcoholism: Clinical and Experimental Research.
Matthews, D.B., Cockroft, J. & Goldowitz, D. (submitted). Genetic mapping of vocalization to acute
footshock using B6.AJ consomic and B6.D2 congenic mouse strains. Behavior Genetics.
Matthews, D.B., Morrow, A.L., O’Buckley, T., Berry, R.B., Mittleman, G., Goldowitz, D., Tokunaga,
S. & Silvers, J.M. (submitted). The effect of acute mild footshock on ethanol self-administration
and plasma corticosterone levels in three commonly used mouse strains. Alcohol.
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Ph.D. Graduates
Janelle Silvers, 2005
Current position, Post-Doctoral researcher, University of South Carolina
Sayaka Tokunaga, 2005
Current position, Post-Doctoral researcher, University of Memphis
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Graduate Commitee
Masters Committee
Sarah Hoffman (Chair), 2001
Sayaka Tokunaga (Chair), 2002
Janelle Silvers (Chair), 2002
Andrea Booth, 2006
Ray Berry (Chair), 2004
Kristy Tinsley (Chair), 2006
Doctoral Committee
Mary Houts, 2000
Bonnie Nagel, 2002
Sayaka Tokunaga (Chair), 2005
Janelle Silvers (Chair), 2005
Carrie Van Brunt (2002)
Melissa Duncan-Fallon (2002)
Jeri Bryant (student at University of Tennessee Health Science Center)
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Undergraduate Commitee
Brad Pounders, University College, Chair, 2001.
Jana Skeen, University College, Chair, 2003.
Lindsey Rice, Psychology Honors Program, reader, 2006.
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Presentations
Renner, M.J., Matthews, D.B. & Pierre, P.J. Factors influencing object investigation in rats: a cumulative
analysis. Presentation at the Psychonomic Society, November 1992.
Best, P.J. & Matthews, D.B. Acute ethanol alters hippocampal “place cells”. Presentation at the 6th annual
Midwestern Hippocampal Conference, June 1994.
Best, P.J., Simson, P.E. & Matthews, D.B. Acute ethanol alters hippocampal place cells. Presentation at
the “Effects of Acute Ethanol on Brain Limbic Mechanisms”, Symposium at the annual Research Society
on Alcoholism, June 1995.
Matthews, D.B. & Dietz-Uhler, B. The effects of political advertisements on political-group identity.
Presentation at the “Current Applications of Social Identity Theory” symposium, Eastern Psychological
Association, March 1996.
Best, P.J., Matthews, D.B. & Simson, P.E. Brain mechanisms of alcohol induced spatial cognitive deficits.
Invited paper. Midwestern Psychological Association, May 1996.
Matthews, D.B. Spatial learning and septal electrophysiology. Fetal Alcohol Research Group, June 1996.
Matthews, D.B. Effect of ethanol on spatial cognitive processing. Presentation at the “Ethanol and the
hippocampal system: Behavior to molecular biology” symposium at the annual American Psychological
Society meeting, May 1998. (Symposia organizer).
Matthews, D.B. Neurosteriods contribute to electrophysiological effects of ethanol in the medial septal
nucleus. Presentation at the “Neurosteriods mediate pharmacological effects of ethanol: A new
mechanism of ethanol action?” symposium at the annual Research Society on Alcoholism, June 1999.
Matthews, D.B., Van Doren, M.J. & Morrow, A.L. Ethanol inhibition of medial septal/diagonal band of Broca
spontaneous neural activity is modulated by allopregnanolone. Ethanol and Cell Signaling symposium,
American Society for Biochemistry and Molecular Biology, October 1999.
Matthews, D.B., Ethanol impairs cognitive processing. Symposium at the annual Research Society on
Alcoholism, June, 2000. (Symposia organizer and chair).
Matthews, D.B. Neurosteroids mimic and may contribute to effects of ethanol on cognitive performance in
rats. Ethanol Sensitivity of GABAA Receptors In Vitro and In Vivo, Research Society on Alcoholism
Poster Discussion, June, 2001.
Matthews, D.B. Development of a high throughput ethanol screen to test mice with single base pair mutations.
Presentation at the “Use of Genetic and Neurobiological Screens for Understanding the Basis of Alcoholism”
symposium at the annual Research Society on Alcoholism, June, 2001.
Matthews, D.B. Impairments in spatial cognitive processing: Ethanol, allopregnanolone and the hippocampus.
Symposium at the European Behavioural Pharmacology Society and European Brain and Behaviour Society,
September, 2001
Matthews D.B., Tokunaga, S., Silvers, J.M. & Morrow A.L. Steroid neurogenesis is critical for ethanol
induced cognitive impairments to moderate ethanol doses. Symposium at the International Behavioral
Neuroscience Meeting, April 2003.
Matthews, D.B. Steroidogenesis is critical for spatial memory impairments produced by moderate doses of
ethanol. Research Society on Alcoholism, 2003. Plenary Lecture.
Matthews, D.B. Neuroactive steroids and ethanol-induced decreases in spatial cognitive processing. 31st
International Medical Advisory Group, October, 2003.
Matthews, D.B., Lu, L., Chesler, E.J. & Williams, R.W. (2004). Use of WEBqtl to identify QTLs associated
with footshock stress and ethanol related behaviors. Symposium at the Research Society on Alcoholism,
June, 2004. (Symposia co-organizer).
Matthews, D.B., Chesler, E., Williams, R.W., Hamre K & Goldowitz G. (2005). High-throughput screening for
ethanol phenotypes. Symposium at the Research Society on Alcoholism, June, 2005.
Morrow, A.L., Penland, P.N., Khisti, R.T., Porcu, P. & Matthews, D.B. (2005). GABAergic neuroactive steroids
contribute to ethanol action in the CNS. Symposium at the Research Society on Alcoholism, June, 2005.
Matthews, D.B., Silvers, J.M., Tokunaga, S. & Morrow, A.L. (2005). Binge alcohol exposure during adolescence
produces behavioral, electrophysiological and biochemical adaptations in hippocampus. Symposium and
platform presentation at the Neurobehavioral Teratology Society, June, 2005.
Matthews, D.B. (2006). Binge alcohol exposure during adolescence produces behavioral, electrophysiological
and biochemical adaptations in hippocampus. Symposium at the Research Society on alcoholism, June, 2006.
(Symposia organizer and chair).
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Selected Posters
Matthews, D.B. & Best, P.J. (1993). Fimbria/fornix lesions affect place learning but not response
learning in the rat. Neuroscience Abstracts, 19, 529.
Matthews, D.B., Vandergriff, J.L., Kendrick, W.T., Simson, P.E. & Best, P.J. (1994). Ethanol impairs
a previously learned spatial response in the rats: comparisons with diazepam and MK-801.
Alcoholism: Clinical and Experimental Research, 18, 520.
Matthews, D.B., Simson, P.E. & Best, P.J. (1994). Ethanol disrupts activity of hippocampal “place cells”
in awake behaving rats. Alcoholism: Clinical and Experimental Research, 18, 520.
Kedrick, W.T., Vandergriff, J.L, Matthews, D.B., Best, P.J. & Simson, P.E. (1994). Ethanol impairs place
learning but not response learning in the rat. Neuroscience Abstracts, 20, 1764.
Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Acute ethanol impairs the use of spatial memory
under a variety of task demands. Alcoholism: Clinical and Experimental Research, 19, 64A.
White, A.M., Matthews, D.B. & Best, P.J. (1995). Fimbria/fornix lesions enhance performance on a
non-spatial trajectory task in the water maze. Neuroscience Abstracts, 21, 1942.
Matthews, D.B., White, A.M., Brush, E.D. & Best, P.J. (1995). Construction of the spatial cognitive map
does not require active exploration of the environment. Neuroscience Abstracts, 21, 2086.
Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Acute administration of ethanol impairs spatial memory.
Alcoholism: Clinical and Experimental Research, 20, 64A.
Dror, I.E., Hays, A., Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Risk taking under the influence
of ethanol. Alcoholism: Clinical and Experimental Research, 20, 111A.
Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Spatial memory deficits in adult rats exposed to ethanol
during gestation. Alcoholism: Clinical and Experimental Research, 20, 73A.
Matthews, D.B. & Best, P.J. (1996). Effect of intra- and extra-maze cues on place field location.
Neuroscience Abstracts 22, 914.
Matthews, D.B, Maier, S.E., Miller, J.A., West, J.R., Best, P.J. & Simson, P.E. (1997). Prenatal
exposure to ethanol differentially alters the effect of an ethanol challenge on spatial cognitive
processing in the rat. Alcoholism: Clinical and Experimental Research, 21, 117A.
Matthews, D.B., Groark, B., Best, P.J. & Simson, P.E. (1997). Opposite effects of two levels of prenatal
exposure to ethanol on responses of medial septal neurons to an ethanol challenge.
Alcoholism: Clinical and Experimental Research, 21, 83A.
Matthews, D.B., Fritschy, J.M., Sieghart, W., Devaud, L.L., and Morrow, A.L. (1997). Differential
effects of 2-week and 6-week chronic ethanol consumption on GABAA receptor peptide expression in
rat hippocampus. Neuroscience Abstracts, 23, 2402.
Grobin, A.C., Matthews, D.B., Sieghart, W., Devaud, L.L. & Morrow, A.L. (1998). Regional variations in
changes in GABAA receptor subunit peptide in the cortex of ethanol dependent rats. Alcoholism:
Clinical and Experimental Research, 22, 10A.
Matthews, D.B., Criswell, H.E., Devaud, L.L., Breese, G.R. & Morrow, A.L. (1998). Chronic ethanol
consumption alters the recovery of spontaneous medial septal activity from GABA microiontophoresis
in rats. Alcoholism: Clinical and Experimental Research, 22, 10A.
Matthews, D.B., Devaud, L.L., Kralic, J.E., Fritschy, J.M., Sieghart, W. & Morrow, A.L. (1998).
Chronic MK-801 administration alters GABA A receptor subunit peptide expression and function in the rat.
Neuroscience Abstracts, 24, 1831.
Van Doren, M.J., Matthews, D.B., Janis, G.C., Grobin, A.C., Devaud, L.L. & Morrow, A.L. (1999).
Neuroactive steroids modulate ethanol effects in brain. Alcoholism: Clinical and Experimental
Research, 23, 14A
Matthews, DB., Van Doren, M.J. & Morrow, A.L. (1999). Finasteride pretreatment prevents ethanol-induced
inhibition of spontaneous neural activity in medial septal/diagonal band of Broca (MS/DB) neurons.
Alcoholism: Clinical and Experimental Research, 23, 15A
Kralic, J.E., Matthews, D.B., Kampov-Polevoi, A.B., Overstreet, D.H., Gause, L.R., McCown, T., & Morrow,
A.L. (1999). Development of ethanol dependence after self-administration in alcohol preferring P rats.
Neuroscience Abstracts, 25, 1078.
Montoya, D., Grobin, A.C., Morrow, A.L., Matthews, D.B., Wilson, W.A. & Swartzwelder, H.S. (1999).
Differential effects of ethanol on muscimol-stimulated 36Cl- Uptake in adolescent vs. adult cortex.
Neuroscience Abstracts, 25, 1577.
Morrow, A.L., Janis, G.C., VanDoren, M.J., Matthews, D.B., Grobin, A.C. & Devaud, L.L. (1999). Ethanol
elevates plasma and brain levels of the neurosteriod 3a-hydroxy-5a-pregnan-20-one: A novel mechanism
of ethanol action. Neuroscience Abstracts, 25, 1808.
VanDoren, M.J., Matthews, D.B. & Morrow, A.L. (1999). The neurosteriod 3a-hydroxy-5a-pregnan-20-one
contributes to behavioral effects of ethanol.